Isaac Asiata is a retired professional football guard. After playing college football with the University of Utah (where he won the Morris Trophy), he was drafted by the Miami Dolphins in the fifth round of the 2017 NFL Draft. He was waived by the Dolphins on September 1, 2018, and was signed to the practice squad. On November 9, 2018, he was promoted to the active roster. On May 16, 2019, Asiata was waived by the Dolphins and placed on injured reserve and released on June 6, 2019.
On July 22, 2019, Asiata was signed by the Buffalo Bills. On July 30, he retired from the NFL.
On April 7, 2020, he became a police officer for the city of Provo, Utah. He is a cousin of NFL running back Matt Asiata.